Peptide Database

Peptide NameEndolysin (EC 3.5.1.28) (N-acetylmuramoyl-L-alanine amidase)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Bacteriolytic activity ▸ Bacteriolytic enzyme

Enzyme / Catalytic activity ▸ Hydrolase

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length153 amino acids

Chemical FormulaC770H1201N217O221S6

DescriptionStandard

        MSKVQFKPRKETKYIFVHCSATRPSQDVGVREIRQWHKEQGWLDVGYHFVIKRDGTIETGRSLEAVGSHVKGYNEVSVGICLVGGIDDQGKPNANFTVAQMESLKAVLKEVGETYPEATIMAHHDVAPKACPSFHVRRWLKGDGLITWYSKEV
    

Molecular Weight17226.48 Da

Isoelectric Point (pI)8.75

Net Charge (pH 7.0)3.10

Net Charge (pH 7.4) 2.44

Charge Density (pH 7.0) 0.0203

GRAVY Index-0.42

Hydrophobic Moment 0.75

Boman Index-0.02

Instability Index38.09

Aliphatic Index 76.34

Aromaticity 0.0915

Extinction Coeff. Reduced 29450.00

Extinction Coeff. Oxidized 29575.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7035.43

LogP -65.54

H-bond Donors 248.0

H-bond Acceptors 237.0

Rotatable Bonds 572.0

Heavy Atoms 1214.0

Ring Count 31.0

Amide Bonds 161.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0382154 VERIFIED: NO

Provenance & Taxonomy

OrganismProvidencia phage PSTRCR_128 [Virus]

FamilyN-acetylmuramoyl-L-alanine amidase 2

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriolytic enzyme Hydrolase Cytolytic Non-hemolytic