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MYP_147750
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Basic Information
Japonicin-1NPb
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Immunology ▸ Innate immune modulation ▸ Mast cell modulation
Membrane / Ion-channel modulation ▸ Calcium channel modulation ▸ Calcium channel inhibitor
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
14 amino acids
C77H135N19O15S3
Standard
Sequence
FVLPLVMCKILRKC
Physicochemical Analysis
1663.21 Da
9.50
2.74
2.50
0.1956
1.44
0.55
0.27
44.49
152.86
0.0714
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
546.77
0.08
21.0
21.0
55.0
114.0
2.0
13.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0080345 VERIFIED: YES
Provenance & Taxonomy
Nanorana parkeri [Animal]
Japonicin
Structure & Mods
Linear peptide with a single intramolecular disulfide-stabilized loop [Linear]
Gene-encoded natural peptide composed of standard L-amino acids [L]
8-14
Bio-Activity Profile
Antioxidant Mast cell degranulation
PaperZ. Lu et al. / Biochimie 92 (2010) 475-481. Novel families of antimicrobial peptides with multiple functions from skin of Xizang plateau frog, Nanorana parkeri Evidence URLhttps://www.uniprot.org/uniprotkb/D0ES74/entry
RECORD: Rec_0121754 VERIFIED: YES
Provenance & Taxonomy
Nanorana parkeri [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Staphylococcus aureus
9.38 μg/mL
MIC
RECORD: Rec_0147257 VERIFIED: YES
Provenance & Taxonomy
Nanorana parkeri [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
8-14
Bio-Activity Profile
Antimicrobial
Staphylococcus aureus ATCC 2592
9.38 μg/mL
MIC
PaperNovel families of antimicrobial peptides with multiple functions from skin of Xizang plateau frog, Nanorana parkeri
RECORD: Rec_0150308 VERIFIED: YES
Provenance & Taxonomy
Xizang plateau [Animal]
Japonicin
33208
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PMID24957834 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24957834/
RECORD: Rec_0152912 VERIFIED: YES
Provenance & Taxonomy
Nanorana parkeri [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PMID20153801 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20153801/
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