Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Standard StatusStandard

Sequence Length75 amino acids

Chemical FormulaC381H610N116O97S6

DescriptionStandard

        WKDLWTVRAVFLLGSLVPRGVSGPNTYIRTAFSTCWGGKGVCRKLCGGNEDYHIFCDVRRLCCVNKKLLNVRVRR
    

Molecular Weight8560.03 Da

Isoelectric Point (pI)9.99

Net Charge (pH 7.0)9.79

Net Charge (pH 7.4) 9.43

Charge Density (pH 7.0) 0.1305

GRAVY Index-0.05

Hydrophobic Moment 0.64

Boman Index-0.05

Instability Index39.79

Aliphatic Index 89.47

Aromaticity 0.1067

Extinction Coeff. Reduced 19480.00

Extinction Coeff. Oxidized 19855.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3466.02

LogP -31.61

H-bond Donors 133.0

H-bond Acceptors 114.0

Rotatable Bonds 280.0

Heavy Atoms 600.0

Ring Count 14.0

Amide Bonds 78.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0252687 VERIFIED: NO

Provenance & Taxonomy

OrganismPanthera leo [Animal]

FamilyDefensin

Structure & Mods

Configdisulfide-stabilized peptide with linear backbone [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin

MethodQualitative functional evidence