Peptide Database

Peptide NameColicin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length165 amino acids

Chemical FormulaC724H1148N204O231S5

DescriptionStandard

        MHNTPARYFPDNGTSTTTDNRGAITHQNGGSSGSGVHWGGGSGHGNGGGQGGNTGSGKPSVALSSGVPALLGPTAGEMGFALSGEAVSTAMAEAFGLLKGPFKFGLWGVALYGILPGEIAKDDPKMMSKIVTSLPADTVTETPASALLLQQSTVRVKQQVVDVVK
    

Molecular Weight16566.41 Da

Isoelectric Point (pI)6.90

Net Charge (pH 7.0)-0.14

Net Charge (pH 7.4) -0.59

Charge Density (pH 7.0) -0.0008

GRAVY Index-0.12

Hydrophobic Moment 0.66

Boman Index0.15

Instability Index31.56

Aliphatic Index 72.12

Aromaticity 0.0545

Extinction Coeff. Reduced 13980.00

Extinction Coeff. Oxidized 13980.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6842.49

LogP -88.87

H-bond Donors 233.0

H-bond Acceptors 240.0

Rotatable Bonds 537.0

Heavy Atoms 1164.0

Ring Count 25.0

Amide Bonds 176.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0348964 VERIFIED: YES

Provenance & Taxonomy

OrganismSalmonella enterica [Bacterium]

Structure & Mods

Configlinear polypeptide/propeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative Antibiotic Bacteriocin Non-hemolytic Non-ribosomal

TargetEscherichia coli