Peptide Database

Peptide NameGlicentin

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Metabolic

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Regulatory peptide ▸ Biological modulation

Regulatory peptide ▸ Biological regulation

Standard StatusStandard

Sequence Length69 amino acids

Chemical FormulaC346H543N107O119S2

DescriptionStandard

        RSLQDTEEKSRSFSAPQTEPLNDLDQMNEDKRHSQGTFTSDYSKYLDSRRAQDFVQWLMNTKRNKNNIA
    

Molecular Weight8169.79 Da

Isoelectric Point (pI)6.79

Net Charge (pH 7.0)-0.14

Net Charge (pH 7.4) -0.42

Charge Density (pH 7.0) -0.0020

GRAVY Index-1.48

Hydrophobic Moment 0.66

Boman Index-0.40

Instability Index94.28

Aliphatic Index 42.46

Aromaticity 0.0870

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8480.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3801.34

LogP -49.48

H-bond Donors 131.0

H-bond Acceptors 122.0

Rotatable Bonds 281.0

Heavy Atoms 574.0

Ring Count 10.0

Amide Bonds 80.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0052430 VERIFIED: YES

Provenance & Taxonomy

OrganismCanis lupus familiaris [Animal]

FamilyGlicentin

Tax ID9615

Structure & Mods

Configlinear peptide [Linear]

Chiralitynoncanonical stereochemical modification [Modified]

Other Mods34:Phosphoserine

Bio-Activity Profile

Function

Hormone Endocrine Metabolic regulation Physiological regulation Receptor modulation

Half-LifeMammalian: 1 hour; Yeast: 2 min; E. coli: 2 min

RECORD: Rec_0074656 VERIFIED: YES

Provenance & Taxonomy

OrganismCanis familiaris [Animal]

FamilyGlucagon

Tax ID9615

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hormone Metabolic

RECORD: Rec_0212541 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide

Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/