Peptide Database

Peptide NameLeptin

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Metabolic

Standard StatusStandard

Sequence Length146 amino acids

Chemical FormulaC706H1189N197O219S4

DescriptionStandard

        VPIRKVQDDTKTLIKTIVTRINDISHTQSVSSKQRVTGLDFIPGLHPLLSLSKMDQTLAIYQQILTSLPSRNVVQISNDLENLRDLLHLLAASKSCPLPQVRALESLESLGVVLEASLYSTEVVALSRLQGSLQDMLRQLDLSPGC
    

Molecular Weight16069.44 Da

Isoelectric Point (pI)6.99

Net Charge (pH 7.0)-0.01

Net Charge (pH 7.4) -0.43

Charge Density (pH 7.0) -0.0001

GRAVY Index0.06

Hydrophobic Moment 0.66

Boman Index0.04

Instability Index45.43

Aliphatic Index 124.11

Aromaticity 0.0205

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3105.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6713.87

LogP -70.36

H-bond Donors 233.0

H-bond Acceptors 226.0

Rotatable Bonds 545.0

Heavy Atoms 1126.0

Ring Count 13.0

Amide Bonds 160.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0034730 VERIFIED: NO

Provenance & Taxonomy

OrganismBos taurus [Animal]

FamilyLeptin

Tax ID9913

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hormone Metabolic

RECORD: Rec_0056068 VERIFIED: NO