Peptide Database

Peptide Namepegdinetanib

Function Ontology

Other / Curated residual function label ▸ Generic enzyme inhibition annotation

Standard StatusStandard

Sequence Length94 amino acids

Chemical FormulaC468H729N125O139S

DescriptionStandard

        GEVVAATPTSLLISWRHPHFPTRYYRITYGETGGNSPVQEFTVPLQPPTATISGLKPGVDYTITVYAVTDGRNGRLLSIPISINYRTEIDKPCQ
    

Molecular Weight10362.61 Da

Isoelectric Point (pI)8.11

Net Charge (pH 7.0)0.93

Net Charge (pH 7.4) 0.59

Charge Density (pH 7.0) 0.0099

GRAVY Index-0.26

Hydrophobic Moment 0.60

Boman Index0.07

Instability Index21.68

Aliphatic Index 83.94

Aromaticity 0.0957

Extinction Coeff. Reduced 14440.00

Extinction Coeff. Oxidized 14440.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4183.47

LogP -42.66

H-bond Donors 146.0

H-bond Acceptors 143.0

Rotatable Bonds 318.0

Heavy Atoms 733.0

Ring Count 22.0

Amide Bonds 99.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0240116 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

FamilyGtoPdb peptide ligand

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Enzyme inhibitory

Targetkinase insert domain receptor (Human)

Activity1 nM

MethodKd