‹ ›
MYP_147528
← PREVIOUS NEXT → BACK
Basic Information
Pyrrhocoricin
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Host defense activity
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Standard
20 amino acids
C105H166N32O29
Standard
Sequence
VDKGSYLPRPTPPRPIYNRN
Physicochemical Analysis
2340.64 Da
10.27
2.73
2.52
0.1366
-1.40
0.40
-0.33
30.64
53.50
0.1000
2980.00
2980.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
988.39
-10.07
33.0
32.0
67.0
166.0
7.0
21.0
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0225633 VERIFIED: YES
Provenance & Taxonomy
European fire bug [Animal]
Pyrrhocoricin
Structure & Mods
head-to-tail cyclic peptide [Cyclic]
noncanonical stereochemical modification [Modified]
Bio-Activity Profile
Antimicrobial
Staphylococcus aureus
>10 μM
MIC
PaperNovel inducible antibacterial peptides from a hemipteran insect, the sap-sucking bug Pyrrhocoris apterus.
RECORD: Rec_0236962 VERIFIED: YES
Provenance & Taxonomy
Pyrrhocoris apterus [Animal]
Pyrrhocoricin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
PaperBiochim Biophys Acta. 1999 Feb 2;1426(3):459-67. | http://www.ncbi.nlm.nih.gov/pubmed/10076062 PMID10076062 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10076062/
RECORD: Rec_0264427 VERIFIED: YES
Provenance & Taxonomy
Pyrrhocoris apterus [other]
Drosocin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Anti-Gram-negative Non-hemolytic
Pseudomonas aeruginosa
PMID8002963;10076062 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8002963/
RECORD: Rec_0273927 VERIFIED: YES
Provenance & Taxonomy
Pyrrhocoris apterus [Animal]
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
L.B and 10 μM in P.B)
5 μM
MIC
PMID10076062;8002963;23562829 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10076062/
RECORD: Rec_0279664 VERIFIED: YES
Provenance & Taxonomy
Pyrrhocoris apterus [Animal]
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
A.tumefaciens
1.25
MIC
PMID10076062 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10076062/
FIRST PREV 1 2 3 4 5 6 NEXT LAST
Showing 5 records on this page · Page 3 of 6