Peptide Database

Peptide NameBeta-defensin 1 (BD-1) (Defensin; beta 1) (cBD-1)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Anti-Candida

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length67 amino acids

Chemical FormulaC339H561N105O82S8

DescriptionStandard

        MRIHYLLFAVLFLFLMPVPGEGGIINTIQRYFCRVRGGRCAALTCLPRETQIGRCSVKGRKCCRTRK
    

Molecular Weight7676.26 Da

Isoelectric Point (pI)10.52

Net Charge (pH 7.0)10.53

Net Charge (pH 7.4) 10.16

Charge Density (pH 7.0) 0.1571

GRAVY Index0.15

Hydrophobic Moment 0.83

Boman Index-0.03

Instability Index28.87

Aliphatic Index 91.64

Aromaticity 0.0896

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3028.77

LogP -25.84

H-bond Donors 117.0

H-bond Acceptors 102.0

Rotatable Bonds 255.0

Heavy Atoms 534.0

Ring Count 10.0

Amide Bonds 69.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0192784 VERIFIED: YES

Provenance & Taxonomy

OrganismChinchilla lanigera [Animal]

FamilyBeta-defensin; Defensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Defensin Antifungal Anti-Candida Anti-Gram-negative Anti-Gram-positive Non-hemolytic

TargetM. catarrhalis (Gram-negative)

RECORD: Rec_0207614 VERIFIED: YES

Provenance & Taxonomy

OrganismChinchilla lanigera [Animal]

FamilyBeta-defensin; Defensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Defensin Antifungal Anti-Candida Anti-Gram-negative Anti-Gram-positive Non-hemolytic

TargetS. pneumoniae (Gram-positive)

RECORD: Rec_0415987 VERIFIED: YES

Provenance & Taxonomy

OrganismChinchilla lanigera [Animal]

FamilyBeta-defensin; Defensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Defensin Antifungal Anti-Candida Anti-Gram-negative Anti-Gram-positive Non-hemolytic

TargetH. influenzae (Gram-negative)