Peptide Database

Peptide NameGnRH

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Neurological / Signaling ▸ Neuropeptide activity ▸ Reproductive neuropeptide

Standard StatusStandard

Sequence Length10 amino acids

Chemical FormulaC52H69N13O16

DescriptionStandard

        EHWSYGLSPG
    

Molecular Weight1132.18 Da

Isoelectric Point (pI)5.24

Net Charge (pH 7.0)-1.08

Net Charge (pH 7.4) -1.30

Charge Density (pH 7.0) -0.1077

GRAVY Index-0.91

Hydrophobic Moment 0.30

Boman Index0.17

Instability Index34.03

Aliphatic Index 39.00

Aromaticity 0.2000

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 6990.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 458.89

LogP -3.94

H-bond Donors 16.0

H-bond Acceptors 16.0

Rotatable Bonds 31.0

Heavy Atoms 81.0

Ring Count 5.0

Amide Bonds 9.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0012261 VERIFIED: YES

Provenance & Taxonomy

OrganismSparus aurata [Animal]

FamilyGnRH

Tax ID8175

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermPyroglutamate

C-TermAmidation

Bio-Activity Profile

Function

Hormone Reproductive neuropeptide

RECORD: Rec_0099129 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide

Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/