Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length85 amino acids

Chemical FormulaC433H666N116O117S9

DescriptionStandard

        MKNLPSNMALSREVFYFGFALFFIVVELPSGSWAGLEYSQSFPGGEIAVCETCRLGRGKCRRTCIESEKIAGWCKLNFFCCRERI
    

Molecular Weight9657.21 Da

Isoelectric Point (pI)8.55

Net Charge (pH 7.0)2.45

Net Charge (pH 7.4) 2.11

Charge Density (pH 7.0) 0.0288

GRAVY Index0.12

Hydrophobic Moment 0.56

Boman Index0.08

Instability Index48.39

Aliphatic Index 74.59

Aromaticity 0.1412

Extinction Coeff. Reduced 13980.00

Extinction Coeff. Oxidized 14355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3743.60

LogP -31.85

H-bond Donors 140.0

H-bond Acceptors 129.0

Rotatable Bonds 317.0

Heavy Atoms 675.0

Ring Count 17.0

Amide Bonds 88.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0323405 VERIFIED: YES

Provenance & Taxonomy

OrganismMus musculus [Animal]

FamilyBeta-defensin; Defensin

Tax ID10090

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfidedisulfide bond; sites not specified

Bio-Activity Profile

Function

Antimicrobial Defensin Non-hemolytic