Peptide Database

Peptide NameProgonadoliberin-1

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Reproductive biology ▸ Reproductive modulation

Standard StatusStandard

Sequence Length59 amino acids

Chemical FormulaC286H449N83O88S2

DescriptionStandard

        QHWSHGLNPGGKRAVMQESAEEIPRSSGYLCDYVAVSPGNKPFRLKDLLTPVAGREIEE
    

Molecular Weight6522.26 Da

Isoelectric Point (pI)6.11

Net Charge (pH 7.0)-1.06

Net Charge (pH 7.4) -1.40

Charge Density (pH 7.0) -0.0179

GRAVY Index-0.64

Hydrophobic Moment 0.60

Boman Index-0.07

Instability Index68.16

Aliphatic Index 72.71

Aromaticity 0.0678

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8480.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2738.58

LogP -28.46

H-bond Donors 94.0

H-bond Acceptors 91.0

Rotatable Bonds 212.0

Heavy Atoms 459.0

Ring Count 12.0

Amide Bonds 62.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0393861 VERIFIED: YES

Provenance & Taxonomy

OrganismClarias gariepinus [Animal]

FamilyProgonadoliberin

Tax ID13013

Structure & Mods

Configlinear peptide [Linear]

Chiralitynoncanonical stereochemical modification [Modified]

N-TermPyroglutamate

Other Mods10:Glycine amide

Bio-Activity Profile

Function

Hormone Endocrine Reproductive regulator

Half-LifeMammalian: 0.8 hour; Yeast: 10 min; E. coli: >10 hour