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MYP_147369
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Basic Information
Unnamed
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Other / Curated residual function label ▸ Generic enzyme inhibition annotation
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
3 amino acids
C17H33N7O4
Standard
Sequence
RPK
Physicochemical Analysis
399.49 Da
11.00
1.76
1.55
0.5864
-3.33
0.43
-1.30
70.87
0.00
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
200.65
-1.73
7.0
6.0
12.0
28.0
1.0
2.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0269938 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
alpha-S1-Casein-derived
9913
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Anticancer Cytotoxic Antileukemic
Lymphocytes
PaperIsolation and characterization of cytotoxic small peptides, α-casecidins, from bovine αs1-casein digested with bovine trypsin | Otani, H. et al. | DOI: 10.1046/j.1344-3941.2003.00135.x Evidence URLhttps://www.uniprot.org/uniprotkb/P02662/entry
RECORD: Rec_0290727 VERIFIED: NO
Provenance & Taxonomy
Capra hircus [Animal]
9925
Structure & Mods
proteolytic peptide fragment [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Angiotensin-converting enzyme (ACE)
PaperIdentification of ACE-inhibitory peptides in different Spanish cheeses by tandem mass spectrometry
RECORD: Rec_0304278 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
9913;0
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Toxic
PaperOtani H., Suzuki H.. Isolation and characterization of cytotoxic small peptides, alpha-casecidins, from bovine alpha s1-casein digested with bovine trypsin. Anim. Sci. J., 74, 427-435, 2003.
RECORD: Rec_0325067 VERIFIED: YES
Provenance & Taxonomy
Ovis aries [Animal]
Casein-derived peptide
9940
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Enzyme inhibitory ACE inhibitory
Angiotensin-I converting enzyme
36.68 ± 0.13 μM
IC50
RECORD: Rec_0376050 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
9913;0
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Anticancer
PaperOtani H., Suzuki H.. Isolation and characterization of cytotoxic small peptides, alpha-casecidins, from bovine alpha s1-casein digested with bovine trypsin. Anim. Sci. J., 74, 427-435, 2003.
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