Peptide Database

Peptide NameSalt-resistant hBD-28

Function Ontology

Antimicrobial

Venom / Toxin ▸ General toxin ▸ Toxicity

Standard StatusStandard

Sequence Length39 amino acids

Chemical FormulaC195H338N64O49S6

DescriptionStandard

        ARLKKCFNKVTGYCRKKCKVGERYEIGCLSGKLCCRRKK
    

Molecular Weight4555.56 Da

Isoelectric Point (pI)10.00

Net Charge (pH 7.0)11.73

Net Charge (pH 7.4) 11.44

Charge Density (pH 7.0) 0.3008

GRAVY Index-0.77

Hydrophobic Moment 0.60

Boman Index-0.41

Instability Index14.99

Aliphatic Index 57.44

Aromaticity 0.0769

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1911.41

LogP -18.96

H-bond Donors 77.0

H-bond Acceptors 67.0

Rotatable Bonds 165.0

Heavy Atoms 314.0

Ring Count 3.0

Amide Bonds 39.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0202730 VERIFIED: YES

Provenance & Taxonomy

OrganismSynthetic construct [Synthetic]

FamilyDefensin

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Toxicity

Targetless than 10% hemolysis up to 120 ug/ml (little hemo.lytic). Also, ~90% smooth muscle cells survived up to 120 ug/ml