Peptide Database

Peptide NamePREDICTED: neutrophil antibiotic peptide NP-2-like [Rattus norvegicus].

Function Ontology

Antimicrobial

Antimicrobial ▸ Antifungal

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length57 amino acids

Chemical FormulaC252H408N76O84S7

DescriptionStandard

        MKDQDISISFGGDKGTALQNADVKSGVTCYCRISCQFGERLSGSCRSGGVTYPLCCR
    

Molecular Weight6070.85 Da

Isoelectric Point (pI)8.28

Net Charge (pH 7.0)1.44

Net Charge (pH 7.4) 1.13

Charge Density (pH 7.0) 0.0253

GRAVY Index-0.22

Hydrophobic Moment 0.61

Boman Index-0.05

Instability Index31.15

Aliphatic Index 59.82

Aromaticity 0.0702

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2611.41

LogP -35.93

H-bond Donors 99.0

H-bond Acceptors 93.0

Rotatable Bonds 204.0

Heavy Atoms 419.0

Ring Count 5.0

Amide Bonds 60.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0070735 VERIFIED: NO

Provenance & Taxonomy

OrganismRattus norvegicus [Animal]

Tax ID10116

Structure & Mods

ConfigSingle-chain peptide backbone represented as a linear sequence entry [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial

RECORD: Rec_0389445 VERIFIED: YES

Provenance & Taxonomy

OrganismRattus norvegicus [Animal]

FamilyAlpha-defensin; Defensin

Tax ID10116

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfidedisulfide bond; sites not specified

Bio-Activity Profile

Function

Antimicrobial Defensin Antifungal Non-hemolytic