Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length78 amino acids

Chemical FormulaC395H618N110O106S10

DescriptionStandard

        MALIRRTFYFVFAMFFILVQQPSGCQAGLDFSEPFPSGKFAVCESCKLGRGKCRKECLENEKPDGSCRLNFLCCRQRI
    

Molecular Weight8924.46 Da

Isoelectric Point (pI)8.90

Net Charge (pH 7.0)4.43

Net Charge (pH 7.4) 4.08

Charge Density (pH 7.0) 0.0568

GRAVY Index-0.03

Hydrophobic Moment 0.49

Boman Index-0.02

Instability Index58.03

Aliphatic Index 66.28

Aromaticity 0.1282

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1990.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3493.51

LogP -31.96

H-bond Donors 129.0

H-bond Acceptors 121.0

Rotatable Bonds 297.0

Heavy Atoms 621.0

Ring Count 14.0

Amide Bonds 83.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0121144 VERIFIED: NO

Provenance & Taxonomy

OrganismRhinopithecus bieti [Animal]

FamilyDefensin

Tax ID61621

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence

RECORD: Rec_0139114 VERIFIED: NO