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MYP_147273
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Basic Information
Nigroain-B-MS1
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Membrane / Ion-channel modulation ▸ Calcium channel modulation ▸ Calcium channel inhibitor
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
21 amino acids
C108H169N31O28S3
Standard
Sequence
CVVSSGWKWNYKIRCKLTGNC
Physicochemical Analysis
2445.88 Da
9.42
3.73
3.47
0.1774
-0.25
0.42
-0.03
9.31
64.76
0.1429
12490.00
12615.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
983.96
-9.29
39.0
35.0
79.0
170.0
5.0
22.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0132081 VERIFIED: YES
Provenance & Taxonomy
Sylvirana maosonensis [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Enterococcus faecalis 981
PMID28402481 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28402481/
RECORD: Rec_0167387 VERIFIED: YES
Provenance & Taxonomy
Sylvirana maosonensis [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
human red blood cells
8.6 % hemolysis at 200 μM
Hemolysis
PMID28402481 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28402481/
RECORD: Rec_0209514 VERIFIED: YES
Provenance & Taxonomy
Hylarana maosuoensis [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antioxidant
Staphylococcus aureus ATCC 25923
4.7 μM
MIC
PaperIdentification and functional analyses of novel antioxidant peptides and antimicrobial peptides from skin secretions of four East Asian frog species. PMID28402481 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28402481/
RECORD: Rec_0250363 VERIFIED: YES
Provenance & Taxonomy
Hylarana maosuoensis [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antioxidant
N. asteroides 201118
18.8 μM
MIC
PaperIdentification and functional analyses of novel antioxidant peptides and antimicrobial peptides from skin secretions of four East Asian frog species. PMID28402481 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28402481/
RECORD: Rec_0328599 VERIFIED: YES
Provenance & Taxonomy
Sylvirana maosonensis [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Staphylococcus aureus ATCC 25923
4.7 μM
MIC
PMID28402481 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28402481/
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