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MYP_147273
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Basic Information
Nigroain-B-MS1
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Membrane / Ion-channel modulation ▸ Calcium channel modulation ▸ Calcium channel inhibitor
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
21 amino acids
C108H169N31O28S3
Standard
Sequence
CVVSSGWKWNYKIRCKLTGNC
Physicochemical Analysis
2445.88 Da
9.42
3.73
3.47
0.1774
-0.25
0.42
-0.03
9.31
64.76
0.1429
12490.00
12615.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
983.96
-9.29
39.0
35.0
79.0
170.0
5.0
22.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0012879 VERIFIED: YES
Provenance & Taxonomy
Sylvirana maosonensis [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Candida glabrata 090902
PMID28402481 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28402481/
RECORD: Rec_0073135 VERIFIED: YES
Provenance & Taxonomy
Sylvirana maosonensis [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Candida albicans ATCC 10231
PMID28402481 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28402481/
RECORD: Rec_0093198 VERIFIED: YES
Provenance & Taxonomy
Hylarana maosonensis [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0098445 VERIFIED: YES
Provenance & Taxonomy
Hylarana maosuoensis [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antioxidant Anti-Gram-positive
Staphylococcus aureus
4.7 μM
MIC
RECORD: Rec_0110731 VERIFIED: YES
Provenance & Taxonomy
Sylvirana maosonensis [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Klebsiella pneumoniae 08040724
PMID28402481 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28402481/
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