Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length182 amino acids

Chemical FormulaC907H1423N247O243S10

DescriptionStandard

        VAHEPMLLLALTDFVANSAAFTYFTAGALHRNISSDMIPRRFPLQLKTKSMEVFAPQLQKYYPDHPMELHLSARKQPLFSCRPDALHGALFSSAEAFVVLPNATRVPAFLLNIDANVTGKPTISRNRLGGTVSLKGMGACPMPGSRGLSVPQVKRLENLLKFSLWLFGVPWANSECCPHPVP
    

Molecular Weight19996.16 Da

Isoelectric Point (pI)9.55

Net Charge (pH 7.0)7.23

Net Charge (pH 7.4) 6.63

Charge Density (pH 7.0) 0.0397

GRAVY Index0.05

Hydrophobic Moment 0.57

Boman Index0.11

Instability Index49.24

Aliphatic Index 89.01

Aromaticity 0.0879

Extinction Coeff. Reduced 15470.00

Extinction Coeff. Oxidized 15720.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7679.24

LogP -84.04

H-bond Donors 264.0

H-bond Acceptors 266.0

Rotatable Bonds 632.0

Heavy Atoms 1407.0

Ring Count 42.0

Amide Bonds 194.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0016062 VERIFIED: NO

Provenance & Taxonomy

OrganismThinocorus orbignyianus [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria