MYP_147266
Basic Information
Ovine corticotropic releasing factor
Hormonal / Endocrine Hormone peptide
Neurological / Signaling Neuromodulation
Neurological / Signaling Neuropeptide activity Neuropeptide
Neurological / Signaling Neuropeptide activity Stress-related neuropeptide
Regulatory peptide Biological modulation
Standard
41 amino acids
C205H338N58O64S
Standard
Sequence
SQEPPISLDLTFHLLREVLEMTKADQLAQQAHSNRKLLDIA
Physicochemical Analysis
4671.29 Da
5.40
-2.36
-2.67
-0.0575
-0.32
0.65
-0.04
34.04
111.95
0.0244
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1983.34
-18.59
66.0
65.0
159.0
328.0
5.0
45.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0091779 VERIFIED: YES
Provenance & Taxonomy
Ovis aries [Animal]
ACTH
9940
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Diagnostic
Radioimmunoassay and HPLC analysis
Intravenous administration to human plasma, in vivo; 744 s
RECORD: Rec_0172951 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]; Rattus norvegicus [Animal]
GHRH/CRF
9606;10116
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
ACTH release stimulation
Radioimmunoassay
Rhesus monkey plasma, in vivo; 1740 s
RECORD: Rec_0389667 VERIFIED: YES
Provenance & Taxonomy
Ovis aries [Animal]
Sauvagine/corticotropin-releasing factor/urotensin I
9940
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Hormone Stress-related neuropeptide
RECORD: Rec_0391891 VERIFIED: NO
Provenance & Taxonomy
Ovis aries [Animal]
9940
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Hormone
RECORD: Rec_0391981 VERIFIED: YES
Provenance & Taxonomy
Ovis aries [Animal]; synthetic construct [Synthetic]
CRH
9940;32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Diagnostic Endocrine stimulation test
CRH receptor / pituitary corticotroph axis
Clinical/Human: Plasma half-lives for IR-corticorelin are 11.6 ± 1.5 min (mean ± SE) for the fast component and 73 ± 8 min for the slow component.
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