Peptide Database

Peptide NameColicin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length587 amino acids

Chemical FormulaC2665H4274N802O876S5

DescriptionStandard

        MSGGDGRGHNTGAHSTSGNINGGPTGLGVSGGASDGSGWSSENNPWGGGSGSGIHWGGGSGRGNGGGNGNSGGGSGTGGNLSAVAAPVAFGFPALSTPGAGGLAVSISASELSAAIAGIIAKLKKVNLKFTPFGVVLSSLIPSEIAKDDPNMMSKIVTSLPADDITESPVSSLPLDKATVNVNVRVVDDVKDERQNISVVSGVPMSVPVVDAKPTERPGVFTASIPGAPVLNISVNNSTPAVQTLSPGVTNNTDKDVRPAGFTQGGNTRDAVIRFPKDSGHNAVYVSVSDVLSPDQVKQRQDEENRRQQEWDATHPVEVAEREYENARAELEAENKNVHSLQVALDGLKNTAEGLALSDAGRHPLTSSESRFVAVPGYSGGGVHFDSTATVDSRDRLNSLLSLGGAAYVNNVLELGEVSAPTEDGLKVGNAIKNAMIEVYDKLRQRLITRQNEINHAQVSLNTAIESRNKKEEKKRSAENKLNEERNKPRKGTKDYGHDYHPAPETEEIKGLGDIKKGIPKTPKQNGGGKRKRWIGDKGRKIYEWDSQHGELEGYRASDGQHLGSFDPKTGKQLKGPDPKRNIKKYL
    

Molecular Weight61725.62 Da

Isoelectric Point (pI)7.25

Net Charge (pH 7.0)0.72

Net Charge (pH 7.4) -0.31

Charge Density (pH 7.0) 0.0012

GRAVY Index-0.61

Hydrophobic Moment 0.73

Boman Index-0.06

Instability Index41.43

Aliphatic Index 72.74

Aromaticity 0.0443

Extinction Coeff. Reduced 47900.00

Extinction Coeff. Oxidized 47900.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0070661 VERIFIED: NO

Provenance & Taxonomy

OrganismEscherichia coli [Bacterium]

FamilyColicin/Bacteriocin

Tax ID585034

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Anti-Gram-negative Non-hemolytic

TargetEscherichia coli (Gram-negative)

MethodQualitative functional evidence