Peptide Database

Peptide NameD-LAK80-HP13

Function Ontology

Anticancer

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antiparasitic ▸ Antimalarial

Antiparasitic ▸ Antiprotozoal

Antiparasitic ▸ Antiprotozoal ▸ Antimalarial ▸ Anti-Plasmodium

Antiparasitic ▸ General antiparasitic ▸ Antiparasitic

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Standard StatusStandard

Sequence Length25 amino acids

Chemical FormulaC133H230N38O26

DescriptionStandard

        KKALAKALKHWLPALHKLAKALAKK
    

Molecular Weight2777.49 Da

Isoelectric Point (pI)10.85

Net Charge (pH 7.0)7.93

Net Charge (pH 7.4) 7.61

Charge Density (pH 7.0) 0.3171

GRAVY Index-0.19

Hydrophobic Moment 0.66

Boman Index-0.05

Instability Index31.47

Aliphatic Index 121.60

Aromaticity 0.0400

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1034.24

LogP -3.36

H-bond Donors 36.0

H-bond Acceptors 36.0

Rotatable Bonds 98.0

Heavy Atoms 197.0

Ring Count 5.0

Amide Bonds 24.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0412014 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

Hemolytic

TargetErythrocytes

Activity8.61 ± 0.35 μM

MethodHC50

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