Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length78 amino acids

Chemical FormulaC393H615N109O107S8

DescriptionStandard

        MALSRKTFSFFFVLLFILAQLTSEGQAGLDYSQSFPGGEFAVCEPCRLGRGKCRKVCLENEKISGNCKLNYFCCRHRI
    

Molecular Weight8835.27 Da

Isoelectric Point (pI)8.98

Net Charge (pH 7.0)4.53

Net Charge (pH 7.4) 4.14

Charge Density (pH 7.0) 0.0580

GRAVY Index0.04

Hydrophobic Moment 0.63

Boman Index0.03

Instability Index31.17

Aliphatic Index 76.28

Aromaticity 0.1282

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3501.26

LogP -33.01

H-bond Donors 130.0

H-bond Acceptors 121.0

Rotatable Bonds 296.0

Heavy Atoms 617.0

Ring Count 13.0

Amide Bonds 83.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0163503 VERIFIED: NO

Provenance & Taxonomy

OrganismOryctolagus cuniculus [Animal]

FamilyDefensin

Tax ID9986

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence