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MYP_147151
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Basic Information
Temporin F
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antiparasitic ▸ General antiparasitic ▸ Antiparasitic
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Standard
13 amino acids
C68H116N14O15
Standard
Sequence
FLPLIGKVLSGIL
Physicochemical Analysis
1369.73 Da
8.75
0.76
0.55
0.0584
1.85
0.50
0.67
19.27
202.31
0.0769
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
449.98
0.28
15.0
16.0
44.0
97.0
2.0
12.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0254346 VERIFIED: YES
Provenance & Taxonomy
Rana temporaria [Animal]
Temporin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antiparasitic Anti-Gram-negative Anti-Gram-positive Non-hemolytic
Gram-negative and Gram-positive bacteria
PMID9022710;34235566;25668079;29349894 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/9022710/
RECORD: Rec_0292731 VERIFIED: YES
Provenance & Taxonomy
Rana temporaria [Animal]
Temporin
8407
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
Amidation
It differs from temporin A only at one residue (K vs. R). Chemical modification: C-terminal amidated
Bio-Activity Profile
Antimicrobial Anticancer Antiparasitic
Cancer: It showed antiproliferative activity to cancer cells: MCF-7
49.75 μM
IC50
PaperTemporins, antimicrobial peptides from the European red frog Rana temporaria.
RECORD: Rec_0305905 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Temporin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial
PaperSimmaco M., Mignogna G., Canofeni S., Miele R., Mangoni M. L., Barra D.. Temporins, antimicrobial peptides from the European red frog Rana temporaria. Eur.J.Biochem., 242, 788-792.
RECORD: Rec_0326670 VERIFIED: YES
Provenance & Taxonomy
Rana temporaria [Animal]
Temporin
8407
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
Amidation
It differs from temporin A only at one residue (K vs. R). Chemical modification: C-terminal amidated
Bio-Activity Profile
Antimicrobial Anticancer Antiparasitic
Enterobacter cloacae beta12
>128 μM
MIC
PaperTemporins, antimicrobial peptides from the European red frog Rana temporaria.
RECORD: Rec_0334126 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Temporin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial
Enterococcus faecalis ATCC29212
20.9 μM
MIC
PMID10940378 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10940378/
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