Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length50 amino acids

Chemical FormulaC219H340N60O71S7

DescriptionStandard

        CPGDAHGPDICTQGGGLCRVGSCVSGEYLAHYCFEPVILCCKNLSPATTE
    

Molecular Weight5173.86 Da

Isoelectric Point (pI)5.01

Net Charge (pH 7.0)-3.12

Net Charge (pH 7.4) -3.54

Charge Density (pH 7.0) -0.0624

GRAVY Index0.14

Hydrophobic Moment 0.46

Boman Index0.17

Instability Index55.26

Aliphatic Index 70.20

Aromaticity 0.0600

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2033.86

LogP -24.32

H-bond Donors 75.0

H-bond Acceptors 77.0

Rotatable Bonds 159.0

Heavy Atoms 357.0

Ring Count 9.0

Amide Bonds 51.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0132101 VERIFIED: YES

Provenance & Taxonomy

OrganismAcanthis flammea [Animal]

FamilyDefensin

Tax ID54769

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

PaperLocus-specific protocol for nine different innate immune genes (antimicrobial peptides: β-defensins) across passerine bird species reveals within-species coding variation and a case of trans-species polymorphisms [PMID:21676198] PMID21676198 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21676198/

RECORD: Rec_0274554 VERIFIED: NO

Provenance & Taxonomy

OrganismCarduelis flammea [Animal]

FamilyDefensin

Structure & Mods

ConfigSingle-chain peptide backbone represented as a linear sequence entry [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial

RECORD: Rec_0281050 VERIFIED: YES

Provenance & Taxonomy

OrganismSpinus spinus [Animal]

FamilyDefensin

Tax ID160760

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

PaperLocus-specific protocol for nine different innate immune genes (antimicrobial peptides: β-defensins) across passerine bird species reveals within-species coding variation and a case of trans-species polymorphisms [PMID:21676198] PMID21676198 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21676198/

RECORD: Rec_0339811 VERIFIED: NO

Provenance & Taxonomy

OrganismSpinus spinus [Animal]

FamilyDefensin

Structure & Mods

ConfigSingle-chain peptide backbone represented as a linear sequence entry [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial