Peptide Database

Peptide NameCircular bacteriocin; circularin A uberolysin family

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length89 amino acids

Chemical FormulaC405H669N103O121S2

DescriptionStandard

        MIGFLGTVTGDISVTSTGFSGQSSFLASKLGLTNLSANRIIYLIDTGSTIMTIVSIVTAVTGAGLIAAGGIAGIKYVIKKQGKDKAAAW
    

Molecular Weight8981.39 Da

Isoelectric Point (pI)9.78

Net Charge (pH 7.0)3.50

Net Charge (pH 7.4) 3.27

Charge Density (pH 7.0) 0.0393

GRAVY Index0.68

Hydrophobic Moment 0.55

Boman Index0.33

Instability Index-0.79

Aliphatic Index 114.04

Aromaticity 0.0674

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8480.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3567.02

LogP -38.38

H-bond Donors 128.0

H-bond Acceptors 127.0

Rotatable Bonds 302.0

Heavy Atoms 631.0

Ring Count 7.0

Amide Bonds 92.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0407637 VERIFIED: NO

Provenance & Taxonomy

OrganismBacillus thuringiensis subsp. higo [Bacterium]

FamilyCircular bacteriocin

Structure & Mods

Configcyclic peptide topology reported [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Bacteriocin Non-hemolytic Non-ribosomal