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MYP_147118
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Basic Information
beta-casomorphin-7 immunomodulating
Anticancer
Anticancer ▸ Anti-breast cancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Enzyme modulation ▸ Enzyme inhibition ▸ BChE Inhibitory
Hemostasis ▸ Antithrombotic activity
Immunology ▸ Immune modulation ▸ Immunomodulatory activity
Membrane / Ion-channel modulation ▸ Calcium channel modulation ▸ Calcium channel inhibitor
Neurological / Signaling ▸ Analgesic/opioid activity ▸ Opioid
Neurological / Signaling ▸ Analgesic/opioid activity ▸ Opioid agonist
Neurological / Signaling ▸ Analgesic/opioid activity ▸ Opioid antagonist
Neurological / Signaling ▸ Analgesic/opioid activity ▸ Opioid receptor ligand
Neurological / Signaling ▸ Neuroactive peptide
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide
Other / Curated residual function label ▸ Generic enzyme inhibition annotation
Sensory / Food function ▸ Taste-active peptide
Sensory / Food function ▸ Taste-active peptide ▸ Bitter peptide
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
7 amino acids
C41H55N7O9
Standard
Sequence
YPFPGPI
Physicochemical Analysis
789.92 Da
5.52
-0.24
-0.45
-0.0344
0.11
0.25
0.52
81.23
55.71
0.2857
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
231.78
0.69
6.0
9.0
16.0
57.0
5.0
6.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0233781 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
Casomorphin
9913
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Opioid receptor ligand Mucin secretagogue Opioid antagonist
Mucin secretion assay
PaperEffects of peptides derived from dietary proteins on mucus secretion in rat jejunum | Claustre, J. et al. | DOI: 10.1152/ajpgi.00535.2001 Evidence URLhttps://www.uniprot.org/uniprotkb/P02666/entry
RECORD: Rec_0236886 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Casomorphin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antioxidant
PaperAmigo L., Mart¨ªnez-Maqueda D., Hern¨¢ndez-Ledesma B.. In silico and in vitro analysis of multifunctionality of animal food-derived peptides. Foods, 9, 991, 2020.
RECORD: Rec_0238103 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
ACE-inhibitory peptide
9913
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive
PaperBioactive peptides derived from milk proteins and their health beneficial potentials: an update. PMID21773582 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21773582/
RECORD: Rec_0295898 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
Casomorphin
9913
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Opioid receptor ligand
PaperMilk Bioactive Peptides and β-Casomorphins Induce Mucus Release in Rat Jejunum | Trompette, A. et al. | DOI: 10.1093/jn/133.11.3499 Evidence URLhttps://www.uniprot.org/uniprotkb/P02666/entry
RECORD: Rec_0328510 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
beta-Casein-derived
9913
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antioxidant Macrophage-modulating
Caco-2 cells
PaperIn Silico and In Vitro Analysis of Multifunctionality of Animal Food-Derived Peptides | Amigo, L. et al. | DOI: 10.3390/foods9080991 Evidence URLhttps://www.uniprot.org/uniprotkb/P02666/entry
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