Peptide Database

Peptide NameLantibiotic

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Standard StatusStandard

Sequence Length60 amino acids

Chemical FormulaC274H426N70O93S6

DescriptionStandard

        MKQFNLEALGAIEDISDDELMVITGAVSVIDAQASGGVFCTVSHECHYNSVSPSSWLTCC
    

Molecular Weight6381.12 Da

Isoelectric Point (pI)4.07

Net Charge (pH 7.0)-7.35

Net Charge (pH 7.4) -7.74

Charge Density (pH 7.0) -0.1225

GRAVY Index0.34

Hydrophobic Moment 0.45

Boman Index0.23

Instability Index62.17

Aliphatic Index 89.33

Aromaticity 0.0667

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7240.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2584.12

LogP -29.40

H-bond Donors 92.0

H-bond Acceptors 94.0

Rotatable Bonds 207.0

Heavy Atoms 443.0

Ring Count 8.0

Amide Bonds 63.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0263970 VERIFIED: NO

Provenance & Taxonomy

OrganismPaenibacillus sp. JNUCC-31 [Bacterium]

FamilyLantibiotic

Structure & Mods

Configthioether-cyclized lantibiotic scaffold [Cyclic]

Chiralitypost-translationally modified ribosomal peptide [Modified]

Other ModsLanthionine/methyllanthionine-type thioether crosslinks are implied by the lantibiotic annotation

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Lantibiotic Anti-Gram-positive

TargetGram-positive bacteria