Peptide Database

Peptide NameColicin-D

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length711 amino acids

Chemical FormulaC3337H5211N901O1047S17

DescriptionStandard

        MSIVLYIHPPHGCYVFKMEINMSDDTTVPTEGVDRGHTMVVWPARPKWGQPGAGTSIGINPDFDPTTGNGWLPEEDGYSEALPTGVPANIQAAINQVKPGYTDGSLMSADLWKLAPAAGYPWDPMVAWDPIFVYFPLQAVSDSNLSAGGLPDTIPVHTRIQDEVHDGAQFISATGSGSQPYSLPVINATSSGAYYTVGQLPGPMAPYTFSFSPTERGELRFPRAEENASGLHPAGFTVGANTTDCIVVFPEGSGLEPLYFAMVVSLPDGPLRQRQEEENQAREKADAEAKAKAEAAAKAREELFAKAGVKTPPEYTPEMVKAAEAALGAAGAMALSQAPNTMQLSVAGNGVWTATGDVVGSLSAAIGRGIAALTASSVGPMVAAASTIFFPPPAGGGSDKVPGRDLDALFALNAQLLTGQNEKIEPGVNSVSLPVRGQLVNSNGQLAIQLLKTGEGLPAAVPVLNAVRDAATGLDRITVPAVAGAPERIILVNPAPPPARPSDTGSQDSVPVTPVHTGTEIKPVETITVTTTPAADIGGLQDFIYWRPDAAGTGVESVYVMLSGPYGETNAKGEYSGRPYNTDKAGGSIQKLDWKTATIDHAGVEKVKLHTGRFTESDANKVMIDRLEKILKGELQPTDVDKRFYTHEIRELERYRSLGIPDGVSPDDNGATWNNTHTATLEDYQLGNDEALLYTREALKAAEEQELRMLK
    

Molecular Weight75248.59 Da

Isoelectric Point (pI)4.78

Net Charge (pH 7.0)-30.44

Net Charge (pH 7.4) -31.41

Charge Density (pH 7.0) -0.0428

GRAVY Index-0.24

Hydrophobic Moment 0.77

Boman Index0.08

Instability Index32.23

Aliphatic Index 79.10

Aromaticity 0.0689

Extinction Coeff. Reduced 86290.00

Extinction Coeff. Oxidized 86415.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0071963 VERIFIED: YES

Provenance & Taxonomy

OrganismSalmonella enterica subsp. enterica serovar Strasbourg [Bacterium]

Structure & Mods

Configlinear polypeptide/propeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative Antibiotic Bacteriocin Non-hemolytic Non-ribosomal

TargetEscherichia coli

RECORD: Rec_0205149 VERIFIED: YES