Peptide Database

Peptide NameBrevinin-2TC

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Standard StatusStandard

Sequence Length29 amino acids

Chemical FormulaC145H236N38O37S4

DescriptionStandard

        GLWESIKNFGKKFALNMMEKIKCKIGGGC
    

Molecular Weight3231.92 Da

Isoelectric Point (pI)9.51

Net Charge (pH 7.0)3.74

Net Charge (pH 7.4) 3.50

Charge Density (pH 7.0) 0.1290

GRAVY Index-0.13

Hydrophobic Moment 0.69

Boman Index0.07

Instability Index12.16

Aliphatic Index 70.69

Aromaticity 0.1034

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5625.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1231.04

LogP -8.80

H-bond Donors 44.0

H-bond Acceptors 45.0

Rotatable Bonds 116.0

Heavy Atoms 224.0

Ring Count 4.0

Amide Bonds 30.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0202535 VERIFIED: YES

Provenance & Taxonomy

OrganismRana kukunoris [Animal]

FamilyBrevinin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)