Peptide Database

Peptide NameInterferon-induced GTP-binding protein Mx1

Function Ontology

Antiviral

Antiviral ▸ Antiviral mechanism ▸ Viral replication inhibition ▸ Replication inhibitor

Standard StatusStandard

Sequence Length662 amino acids

Chemical FormulaC3348H5386N920O1022S20

DescriptionStandard

        MVVSEVDIAKADPAAASHPLLLNGDATVAQKNPGSVAENNLCSQYEEKVRPCIDLIDSLRALGVEQDLALPAIAVIGDQSSGKSSVLEALSGVALPRGSGIVTRCPLVLKLKKLVNEDKWRGKVSYQDYEIEISDASEVEKEINKAQNAIAGEGMGISHELITLEISSRDVPDLTLIDLPGITRVAVGNQPADIGYKIKTLIKKYIQRQETISLVVVPSNVDIATTEALSMAQEVDPEGDRTIGILTKPDLVDKGTEDKVVDVVRNLVFHLKKGYMIVKCRGQQEIQDQLSLSEALQREKIFFENHPYFRDLLEEGKATVPCLAEKLTSELITHICKSLPLLENQIKETHQRITEELQKYGVDIPEDENEKMFFLIDKVNAFNQDITALMQGEETVGEEDIRLFTRLRHEFHKWSTIIENNFQEGHKILSRKIQKFENQYRGRELPGFVNYRTFETIVKQQIKALEEPAVDMLHTVTDMVRLAFTDVSIKNFEEFFNLHRTAKSKIEDIRAEQEREGEKLIRLHFQMEQIVYCQDQVYRGALQKVREKELEEEKKKKSWDFGAFQSSSATDSSMEEIFQHLMAYHQEASKRISSHIPLIIQFFMLQTYGQQLQKAMLQLLQDKDTYSWLLKERSDTSDKRKFLKERLARLTQARRRLAQFPG
    

Molecular Weight75519.43 Da

Isoelectric Point (pI)5.60

Net Charge (pH 7.0)-15.10

Net Charge (pH 7.4) -16.42

Charge Density (pH 7.0) -0.0228

GRAVY Index-0.42

Hydrophobic Moment 0.73

Boman Index-0.06

Instability Index36.64

Aliphatic Index 94.11

Aromaticity 0.0665

Extinction Coeff. Reduced 44350.00

Extinction Coeff. Oxidized 44725.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0104654 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyMx

Tax ID9606

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermAcetylation

Bio-Activity Profile

Function

Antiviral Replication inhibitor Anti-DUGV

TargetDugbe nairovirus(DUGV)

RECORD: Rec_0206739 VERIFIED: YES