Peptide Database

Peptide NameCliotide T36

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antiparasitic ▸ Anthelminthic

Antiparasitic ▸ Anthelminthic ▸ Nematicidal activity

Insecticidal/Pest control ▸ Insecticidal activity

Standard StatusStandard

Sequence Length31 amino acids

Chemical FormulaC139H225N39O40S6

DescriptionStandard

        GVIPCGESCVWIPCISAAIGCSCKKNVCYRN
    

Molecular Weight3274.90 Da

Isoelectric Point (pI)8.33

Net Charge (pH 7.0)1.70

Net Charge (pH 7.4) 1.40

Charge Density (pH 7.0) 0.0549

GRAVY Index0.56

Hydrophobic Moment 0.30

Boman Index0.20

Instability Index23.86

Aliphatic Index 84.84

Aromaticity 0.0645

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7365.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1252.87

LogP -13.59

H-bond Donors 49.0

H-bond Acceptors 48.0

Rotatable Bonds 102.0

Heavy Atoms 224.0

Ring Count 5.0

Amide Bonds 32.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0154331 VERIFIED: NO

Provenance & Taxonomy

OrganismClitoria ternatea [Plant]

FamilyCyclotide

Structure & Mods

Configbackbone-cyclized peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial

RECORD: Rec_0213603 VERIFIED: YES

Provenance & Taxonomy

OrganismClitoria ternatea [Plant]

FamilyCyclotide

Tax ID43366

Structure & Mods

Confighead-to-tail cyclic peptide scaffold [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

DisulfideCysteine-rich scaffold consistent with multiple disulfide bonds in the annotated family

Bio-Activity Profile

Function

Antimicrobial Antibacterial Insecticidal Nematocidal Anthelmintic Anti-Gram-negative

TargetEscherichia coli

RECORD: Rec_0280221 VERIFIED: YES

Provenance & Taxonomy

OrganismClitoria ternatea [Plant]

FamilyCyclotide

Tax ID43366

Structure & Mods

Confighead-to-tail cyclic peptide scaffold [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

DisulfideCysteine-rich scaffold consistent with multiple disulfide bonds in the annotated family

Bio-Activity Profile

Function

Insecticidal Nematocidal Anthelmintic

TargetCaenorhabditis elegans

RECORD: Rec_0288177 VERIFIED: YES

Provenance & Taxonomy

OrganismClitoria ternatea [Plant]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

-

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)