Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Standard StatusStandard

Sequence Length89 amino acids

Chemical FormulaC444H744N128O129S8

DescriptionStandard

        MPLDRSSLLSGYIKLSVLTLAVLVLLAQASPDGWLKRCNYGKGRCRKSCKENERKKERCGEKKICCIPDVKREPTYSVEKQKMTYELNV
    

Molecular Weight10195.96 Da

Isoelectric Point (pI)9.45

Net Charge (pH 7.0)8.45

Net Charge (pH 7.4) 8.11

Charge Density (pH 7.0) 0.0949

GRAVY Index-0.54

Hydrophobic Moment 0.54

Boman Index-0.19

Instability Index36.27

Aliphatic Index 84.27

Aromaticity 0.0562

Extinction Coeff. Reduced 11460.00

Extinction Coeff. Oxidized 11835.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4221.96

LogP -40.40

H-bond Donors 155.0

H-bond Acceptors 146.0

Rotatable Bonds 354.0

Heavy Atoms 709.0

Ring Count 10.0

Amide Bonds 93.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0413974 VERIFIED: NO

Provenance & Taxonomy

OrganismNeovison vison [Animal]

FamilyDefensin

Structure & Mods

Configdisulfide-stabilized peptide with linear backbone [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin

MethodQualitative functional evidence