Peptide Database

Peptide Namegamma5 (p62-p74; E63 and E68)

Function Ontology

Immunology ▸ Immunomodulation ▸ Celiac-immunogenic

Standard StatusStandard

Sequence Length13 amino acids

Chemical FormulaC73H101N17O23

DescriptionStandard

        PEQPFPEQPQQPY
    

Molecular Weight1584.68 Da

Isoelectric Point (pI)4.05

Net Charge (pH 7.0)-2.04

Net Charge (pH 7.4) -2.10

Charge Density (pH 7.0) -0.1567

GRAVY Index-2.12

Hydrophobic Moment 0.34

Boman Index-0.22

Instability Index169.31

Aliphatic Index 0.00

Aromaticity 0.1538

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 630.56

LogP -5.35

H-bond Donors 17.0

H-bond Acceptors 21.0

Rotatable Bonds 43.0

Heavy Atoms 113.0

Ring Count 7.0

Amide Bonds 16.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0041045 VERIFIED: YES

Provenance & Taxonomy

OrganismTriticum aestivum [Plant]

FamilyGliadin

Tax ID4565

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Other ModsDeamidation; Reported substitutions/positions: E63; Reported substitutions/positions: E68

Bio-Activity Profile

Function

Celiac-immunogenic

TargetHuman intestinal T cells / HLA-DQ2

MethodT-cell proliferation assay