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MYP_146847
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Basic Information
HYL-12 (Derived from HYL)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
16 amino acids
C83H157N21O19
Standard
Sequence
GILSSLLKKLKKIIAK
Physicochemical Analysis
1753.26 Da
10.60
4.76
4.54
0.2972
0.56
0.72
0.10
6.92
176.88
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
670.38
-2.73
24.0
24.0
67.0
123.0
0.0
15.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0187659 VERIFIED: YES
Provenance & Taxonomy
Hylaeus signatus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Candida albicans
10 μM
MIC
PMID26998557 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26998557/
RECORD: Rec_0200301 VERIFIED: YES
Provenance & Taxonomy
Hylaeus signatus [Animal]
Structure & Mods
linear peptide [Linear]
all-D amino-acid peptide [D]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Candida albicans
9 μM
MIC
PMID26998557 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26998557/
RECORD: Rec_0240042 VERIFIED: YES
Provenance & Taxonomy
Hylaeus signatus [Animal]
Structure & Mods
linear peptide [Linear]
all-D amino-acid peptide [D]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Pseudomonas aeruginosa 5482
4.5 μM
MIC
PMID26998557 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26998557/
RECORD: Rec_0242093 VERIFIED: YES
Provenance & Taxonomy
Hylaeus signatus [Animal]
Structure & Mods
linear peptide [Linear]
all-D amino-acid peptide [D]
Amidation
Bio-Activity Profile
Hemolytic
Human RBCs
333 μM
LC50
PMID26998557 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26998557/
RECORD: Rec_0311851 VERIFIED: YES
Provenance & Taxonomy
Hylaeus signatus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Staphylococcus epidermidis
1.8 μM
MIC
PMID26998557 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26998557/
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