Peptide Database

Peptide NameSsmTx-1

Function Ontology

Membrane / Ion-channel modulation ▸ Ion channel modulation

Standard StatusStandard

Sequence Length36 amino acids

Chemical FormulaC175H279N45O59S5

DescriptionStandard

        EESMLLSCPDLSCPTGYTCDVLTKKCKRLSDELWDH
    

Molecular Weight4117.68 Da

Isoelectric Point (pI)4.65

Net Charge (pH 7.0)-3.11

Net Charge (pH 7.4) -3.40

Charge Density (pH 7.0) -0.0864

GRAVY Index-0.45

Hydrophobic Moment 0.65

Boman Index-0.09

Instability Index64.75

Aliphatic Index 73.06

Aromaticity 0.0556

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7240.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1671.61

LogP -16.69

H-bond Donors 62.0

H-bond Acceptors 62.0

Rotatable Bonds 135.0

Heavy Atoms 284.0

Ring Count 6.0

Amide Bonds 35.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0268442 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

FamilyGtoPdb peptide ligand

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Ion channel modulation

TargetKv2.1 (Rat)

Activity41.7 nM

MethodIC50