Peptide Database

Peptide NameP5

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antifungal

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Standard StatusStandard

Sequence Length18 amino acids

Chemical FormulaC117H204N34O20

DescriptionStandard

        YIRKIRRFFKKLKKILKK
    

Molecular Weight2407.09 Da

Isoelectric Point (pI)11.78

Net Charge (pH 7.0)9.75

Net Charge (pH 7.4) 9.54

Charge Density (pH 7.0) 0.5418

GRAVY Index-0.86

Hydrophobic Moment 1.08

Boman Index-0.51

Instability Index20.03

Aliphatic Index 108.33

Aromaticity 0.1667

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 946.09

LogP -2.00

H-bond Donors 36.0

H-bond Acceptors 30.0

Rotatable Bonds 91.0

Heavy Atoms 171.0

Ring Count 3.0

Amide Bonds 17.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0390344 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyDefensin

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antifungal Anti-Gram-positive

TargetS. mutans ATCC UA159

Activity64 μg/mL

MethodMIC

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