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MYP_146812
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Basic Information
P5
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
18 amino acids
C117H204N34O20
Standard
Sequence
YIRKIRRFFKKLKKILKK
Physicochemical Analysis
2407.09 Da
11.78
9.75
9.54
0.5418
-0.86
1.08
-0.51
20.03
108.33
0.1667
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
946.09
-2.00
36.0
30.0
91.0
171.0
3.0
17.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0163397 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive
S. sangui ATCC 10556
64 μg/mL
MIC
PMID31520928 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31520928/
RECORD: Rec_0188732 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive
MRSA 18466
8 μg/mL
MIC
PMID31520928 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31520928/
RECORD: Rec_0216213 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive
Staphylococcus aureus ATCC 25923
8 μg/mL
MIC
PMID31520928 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31520928/
RECORD: Rec_0267250 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive
Candida albicans ATCC 5314
32 μg/mL
MIC
PMID31520928 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31520928/
RECORD: Rec_0275773 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Hemolytic
Murine blood [HC10 = 640 microg/mL, HC50 = >640 microg/mL, Percent Hemolysis ± SD Hmax (100%) = 10.27 ± 2.2]
640 μg/mL
HC50
PMID31520928 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31520928/
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