Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length99 amino acids

Chemical FormulaC522H848N140O143S7

DescriptionStandard

        MRLLLITAILLLEFTVTKQLKKCWGEYVQGHCRKICKITEIRQVLCENGRYCCLNILELEARRKITKPPRPKPVTFAYTFPQNEDIYTESYSILKANST
    

Molecular Weight11597.62 Da

Isoelectric Point (pI)9.26

Net Charge (pH 7.0)6.54

Net Charge (pH 7.4) 6.15

Charge Density (pH 7.0) 0.0660

GRAVY Index-0.19

Hydrophobic Moment 0.71

Boman Index-0.04

Instability Index40.96

Aliphatic Index 98.48

Aromaticity 0.0909

Extinction Coeff. Reduced 12950.00

Extinction Coeff. Oxidized 13325.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4607.45

LogP -36.14

H-bond Donors 167.0

H-bond Acceptors 158.0

Rotatable Bonds 389.0

Heavy Atoms 812.0

Ring Count 16.0

Amide Bonds 106.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0108823 VERIFIED: NO

Provenance & Taxonomy

OrganismErinaceus europaeus [Animal]

FamilyBeta-defensin; Defensin

Tax ID9365

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfidedisulfide bond; sites not specified

Bio-Activity Profile

Function

Antimicrobial Defensin Non-hemolytic