Peptide Database

Peptide Name[K7, P8, K11]-IsCT (IsCT analog through amino acids substitution)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antifungal

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Venom / Toxin ▸ General toxin ▸ Toxic

Standard StatusStandard

Sequence Length12 amino acids

Chemical FormulaC76H127N17O13

DescriptionStandard

        ILGKIWKIKKLF
    

Molecular Weight1486.93 Da

Isoelectric Point (pI)10.48

Net Charge (pH 7.0)3.76

Net Charge (pH 7.4) 3.55

Charge Density (pH 7.0) 0.3130

GRAVY Index0.58

Hydrophobic Moment 0.39

Boman Index0.23

Instability Index-10.16

Aliphatic Index 162.50

Aromaticity 0.1667

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 503.29

LogP 2.08

H-bond Donors 18.0

H-bond Acceptors 17.0

Rotatable Bonds 53.0

Heavy Atoms 106.0

Ring Count 3.0

Amide Bonds 11.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0371312 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative

TargetEscherichia coli

Activity2 μM

MethodMIC

RECORD: Rec_0378682 VERIFIED: YES