Peptide Database

Peptide NameCecropin

Function Ontology

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Standard StatusStandard

Sequence Length25 amino acids

Chemical FormulaC128H218N42O35

DescriptionStandard

        GWLKKLGKRIERVGQHTRDATIQTI
    

Molecular Weight2905.36 Da

Isoelectric Point (pI)11.00

Net Charge (pH 7.0)3.85

Net Charge (pH 7.4) 3.59

Charge Density (pH 7.0) 0.1539

GRAVY Index-0.78

Hydrophobic Moment 0.93

Boman Index-0.23

Instability Index33.49

Aliphatic Index 93.60

Aromaticity 0.0400

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1291.42

LogP -12.29

H-bond Donors 47.0

H-bond Acceptors 40.0

Rotatable Bonds 102.0

Heavy Atoms 205.0

Ring Count 3.0

Amide Bonds 26.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0148290 VERIFIED: YES

Provenance & Taxonomy

OrganismDrosophila ficusphila [Animal]

FamilyCecropin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

-

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)