Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length189 amino acids

Chemical FormulaC944H1502N262O256S8

DescriptionStandard

        AHEPMLLLAVTEFVANSAAFTYFTAGALRRNISSDMLPRQFPLQLRTKSMEVFSPQLQERYPDQPMELHLWARRQPLLSCHPDALHGTLFSSAEAFVVLPNASRVPAFLLNIDANVTGKPTITRNRLGGTVRLTGLVPDPELGTPLPALCQAQGLPVPQVKRLETLLKFGLWLFGVPRANSKCCPRPVP
    

Molecular Weight20874.15 Da

Isoelectric Point (pI)9.55

Net Charge (pH 7.0)6.13

Net Charge (pH 7.4) 5.65

Charge Density (pH 7.0) 0.0324

GRAVY Index-0.00

Hydrophobic Moment 0.55

Boman Index0.07

Instability Index57.09

Aliphatic Index 94.97

Aromaticity 0.0741

Extinction Coeff. Reduced 13980.00

Extinction Coeff. Oxidized 14230.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 8152.39

LogP -96.18

H-bond Donors 279.0

H-bond Acceptors 274.0

Rotatable Bonds 658.0

Heavy Atoms 1470.0

Ring Count 41.0

Amide Bonds 204.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0118184 VERIFIED: NO

Provenance & Taxonomy

OrganismEdolisoma coerulescens [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria