Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length66 amino acids

Chemical FormulaC325H531N97O88S9

DescriptionStandard

        MRIFFSISAALILLVHIFSARGGIHREMQCQRMDGRCEAECLSFEVKIGGCRAELTPFCCKKNKNK
    

Molecular Weight7493.87 Da

Isoelectric Point (pI)9.12

Net Charge (pH 7.0)4.63

Net Charge (pH 7.4) 4.20

Charge Density (pH 7.0) 0.0701

GRAVY Index0.04

Hydrophobic Moment 0.45

Boman Index-0.02

Instability Index35.84

Aliphatic Index 81.36

Aromaticity 0.0758

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 375.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3002.20

LogP -27.87

H-bond Donors 112.0

H-bond Acceptors 104.0

Rotatable Bonds 259.0

Heavy Atoms 519.0

Ring Count 8.0

Amide Bonds 69.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0075308 VERIFIED: NO

Provenance & Taxonomy

OrganismUrsus maritimus [Animal]

FamilyDefensin

Tax ID29073

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence

RECORD: Rec_0197778 VERIFIED: NO