Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length81 amino acids

Chemical FormulaC396H665N103O109S7

DescriptionStandard

        SRLQLLPPSVLGLLSTLTLLLPSLLLSVMKCWGTSGRCRATCKESEIFHILCKSEEKCCVNPKYVPVKPASTSLAKIPLQP
    

Molecular Weight8837.60 Da

Isoelectric Point (pI)9.24

Net Charge (pH 7.0)5.49

Net Charge (pH 7.4) 5.13

Charge Density (pH 7.0) 0.0678

GRAVY Index0.30

Hydrophobic Moment 0.53

Boman Index0.12

Instability Index59.66

Aliphatic Index 113.09

Aromaticity 0.0370

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7365.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3335.46

LogP -29.06

H-bond Donors 121.0

H-bond Acceptors 123.0

Rotatable Bonds 288.0

Heavy Atoms 615.0

Ring Count 13.0

Amide Bonds 83.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0223266 VERIFIED: NO

Provenance & Taxonomy

OrganismOryctolagus cuniculus [Animal]

FamilyDefensin

Tax ID9986

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence