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MYP_146651
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Basic Information
Pyr_L7R/R14K
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
20 amino acids
C105H167N33O29
Standard
Sequence
VDKGSYRPRPTPPKPIYNRN
Physicochemical Analysis
2355.65 Da
10.43
3.73
3.51
0.1866
-1.78
0.32
-0.46
12.56
34.00
0.1000
2980.00
2980.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1014.41
-10.98
34.0
33.0
69.0
167.0
7.0
21.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0130653 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Nonpathogenic Escherichia coli MC1041
0.075±0.018
MIC
PMID31209863 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31209863/
RECORD: Rec_0204999 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer
Tumor cells: A431 (<10% Cytotoxicity=10 μM)
PMID31209863 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31209863/
RECORD: Rec_0213812 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Parental Escherichia coli BW25113
0.037±0.008
MIC
PMID31209863 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31209863/
RECORD: Rec_0222457 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Commensal Escherichia coli FVEC 638
0.150±0.034
MIC
PMID31209863 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31209863/
RECORD: Rec_0254905 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Nonpathogenic Escherichia coli JW0013
0.075±0.018
MIC
PMID31209863 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31209863/
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