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MYP_146616
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Basic Information
pBD129
Antimicrobial
Immunology ▸ Immune modulation ▸ Immunomodulatory activity
Immunology ▸ Inflammation modulation ▸ Anti-inflammatory
Standard
173 amino acids
C830H1370N236O260S11
Standard
Sequence
MKLLFPIFASLMLQYQVNTEYFGLGRCVMGLGRCKDHCAVNEKEIDKCKKKKCCIGPKGIQLIKSYLQNEMIRTLEEVAKKNITKNSKVVTPSKYRPLSHLPEIKSTNPFASINTTIIPNGTTVNSTTTNSTTSRRSTHPATSTKSDTKKRRDSPTESPPADSSPIDPADSMT
Physicochemical Analysis
19167.90 Da
9.57
11.71
11.20
0.0677
-0.61
0.76
-0.13
46.15
67.63
0.0462
5960.00
6335.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
8042.29
-102.74
284.0
286.0
644.0
1337.0
24.0
186.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0056415 VERIFIED: YES
Provenance & Taxonomy
Sus scofa [Animal]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Anti-inflammatory Immunomodulatory
Bacillus subtilis
>512 μg/mL
MIC
PaperThe immunomodulatory function of the porcine beta-defensin 129: Alleviate inflammatory response induced by LPS in IPEC-J2 cells.
RECORD: Rec_0069444 VERIFIED: YES
Provenance & Taxonomy
Sus scofa [Animal]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Anti-inflammatory Immunomodulatory
Streptococcus
32 μg/mL
MIC
PaperThe immunomodulatory function of the porcine beta-defensin 129: Alleviate inflammatory response induced by LPS in IPEC-J2 cells.
RECORD: Rec_0149281 VERIFIED: YES
Provenance & Taxonomy
Sus scofa [Animal]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Anti-inflammatory Immunomodulatory
pathogenic Escherichia coli K88+
>512 μg/mL
MIC
PaperThe immunomodulatory function of the porcine beta-defensin 129: Alleviate inflammatory response induced by LPS in IPEC-J2 cells.
RECORD: Rec_0157974 VERIFIED: YES
Provenance & Taxonomy
Sus scofa [Animal]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Anti-inflammatory Immunomodulatory
Salmonella Typhimurium CICC14028
>512 μg/mL
MIC
PaperThe immunomodulatory function of the porcine beta-defensin 129: Alleviate inflammatory response induced by LPS in IPEC-J2 cells.
RECORD: Rec_0217008 VERIFIED: YES
Provenance & Taxonomy
Sus scofa [Animal]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Anti-inflammatory Immunomodulatory
P.pastoris X33
>512 μg/mL
MIC
PaperThe immunomodulatory function of the porcine beta-defensin 129: Alleviate inflammatory response induced by LPS in IPEC-J2 cells.
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