Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length111 amino acids

Chemical FormulaC529H868N144O154S15

DescriptionStandard

        MKSLLFTLAVFMLLAQLVSGNWYVKKCLNDVGICKKKCKPEEMHVKNGWAMCSKQRDCCVPADRRANYPAFCVQTKTTRTSTVTATTATTTLMMTTASMSLMAPTPVSPTG
    

Molecular Weight12190.40 Da

Isoelectric Point (pI)9.47

Net Charge (pH 7.0)8.52

Net Charge (pH 7.4) 8.12

Charge Density (pH 7.0) 0.0767

GRAVY Index0.01

Hydrophobic Moment 0.46

Boman Index0.04

Instability Index36.54

Aliphatic Index 67.66

Aromaticity 0.0631

Extinction Coeff. Reduced 13980.00

Extinction Coeff. Oxidized 14355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4773.52

LogP -51.74

H-bond Donors 175.0

H-bond Acceptors 179.0

Rotatable Bonds 399.0

Heavy Atoms 842.0

Ring Count 16.0

Amide Bonds 117.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0170639 VERIFIED: NO

Provenance & Taxonomy

OrganismGorilla gorilla gorilla [Animal]

FamilyDefensin

Tax ID9593

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence