Peptide Database

Peptide Name[P]BN(6-13)PA [Bombesin antagonist]

Function Ontology

Enzyme modulation ▸ Enzyme inhibition ▸ Growth inhibitors

Standard StatusStandard

Sequence Length8 amino acids

Chemical FormulaC47H64N12O10

DescriptionStandard

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Molecular Weight957.09 Da

Isoelectric Point (pI)6.74

Net Charge (pH 7.0)-0.15

Net Charge (pH 7.4) -0.41

Charge Density (pH 7.0) -0.0191

GRAVY Index0.57

Hydrophobic Moment 0.33

Boman Index0.50

Instability Index-20.65

Aliphatic Index 97.50

Aromaticity 0.2500

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 354.58

LogP -0.66

H-bond Donors 12.0

H-bond Acceptors 11.0

Rotatable Bonds 27.0

Heavy Atoms 69.0

Ring Count 4.0

Amide Bonds 8.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0047008 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

FamilyBombesin

Structure & Mods

Configlinear peptide [Linear]

Chiralitymixed L/D amino-acid peptide [Mixed]

N-TermNone

C-TermAmidation

Other ModsD-residue notation at positions 1; Mixed L/D stereochemistry with D-annotated positions 1

Bio-Activity Profile

Function

Growth inhibitors

Activity0.003 μM

MethodIC50

Half-LifeSCLC cell line NCI-H345, in vitro; 33540 s