Peptide Database

Peptide NamePhoratoxins B

Function Ontology

Anticancer

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length47 amino acids

Chemical FormulaC208H336N66O66S6

DescriptionStandard

        KSCCPTTTARNIYNTCRFGGGSRPICAKLSGCKIISGTKCDSNGWDH
    

Molecular Weight5009.69 Da

Isoelectric Point (pI)9.13

Net Charge (pH 7.0)4.79

Net Charge (pH 7.4) 4.44

Charge Density (pH 7.0) 0.1018

GRAVY Index-0.47

Hydrophobic Moment 0.64

Boman Index-0.09

Instability Index46.64

Aliphatic Index 45.74

Aromaticity 0.0638

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7365.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2144.99

LogP -31.02

H-bond Donors 83.0

H-bond Acceptors 78.0

Rotatable Bonds 163.0

Heavy Atoms 346.0

Ring Count 7.0

Amide Bonds 49.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0166567 VERIFIED: YES

Provenance & Taxonomy

OrganismPhoradendron tomentosum [Plant]

FamilyThionin

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfidemultiple disulfide bonds reported, sites not specified

Bio-Activity Profile

Function

Anticancer Cytotoxic

TargetMice

RECORD: Rec_0289455 VERIFIED: NO

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configtopology not specified [Not included yet]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Anticancer