Peptide Database

Peptide NameUrotensin II

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Neurological / Signaling ▸ Neuropeptide activity ▸ Vasoactive neuropeptide

Standard StatusStandard

Sequence Length12 amino acids

Chemical FormulaC65H90N14O18S2

DescriptionStandard

        GPTSECFWKYCV
    

Molecular Weight1419.62 Da

Isoelectric Point (pI)5.99

Net Charge (pH 7.0)-0.26

Net Charge (pH 7.4) -0.50

Charge Density (pH 7.0) -0.0216

GRAVY Index-0.09

Hydrophobic Moment 0.29

Boman Index0.17

Instability Index55.55

Aliphatic Index 24.17

Aromaticity 0.2500

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7115.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 514.43

LogP -3.33

H-bond Donors 20.0

H-bond Acceptors 20.0

Rotatable Bonds 40.0

Heavy Atoms 99.0

Ring Count 5.0

Amide Bonds 11.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0133561 VERIFIED: YES

Provenance & Taxonomy

OrganismSus scrofa [Animal]

FamilyUrotensin

Tax ID9823

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

-

Half-LifeMammalian: 30 hour; Yeast: >20 hour; E. coli: >10 hour

RECORD: Rec_0270721 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

FamilyUrotensin-2

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide6-11

Bio-Activity Profile

Function

Hormone Vasoactive neuropeptide